Core Molecular Specs & Technical Index

SS-31 peptide, also known as Elamipretide or MTP-131, is a mitochondrial-targeting tetrapeptide with the sequence D-Arg-Dmt-Lys-Phe-NH2. For B2B buyers in cosmetic formulation and laboratory research, this peptide is valued for its targeted bioactivity and high-purity specifications. The core value lies in its ability to support mitochondrial function in cellular models, making it a sought-after ingredient for advanced topical formulations and research applications.

Below are the essential technical specifications that professional buyers must verify before procurement:

• Molecular Formula: C38H51N7O6; Molecular Weight: 709.86 g/mol
• Purity Standard: ≥98% (HPLC), with premium grades reaching ≥99% for research-grade applications
• Solubility: Soluble in water, DMSO, and ethanol; recommended stock solution at 10 mM in DMSO
• Storage Conditions: Lyophilized powder stable at -20°C for 24 months; reconstituted solution stable at -80°C for 6 months
• Appearance: White to off-white lyophilized powder, free of visible particulates

Industry data indicates that over 85% of commercial peptide buyers now require third-party HPLC and mass spectrometry verification for each batch. SS-31 peptide with ≥98% purity and documented stability profiles commands a 30% premium in the cosmetic raw material market, reflecting its specialized application value.

Manufacturing & Quality Control

Reliable SS-31 peptide manufacturing follows a rigorous process to ensure batch-to-batch consistency. The production chain begins with solid-phase peptide synthesis (SPPS) using Fmoc chemistry, followed by cleavage, precipitation, and purification. Each step is documented to meet GMP-like standards for cosmetic raw materials.

Production Process

The synthesis cycle includes resin loading, sequential amino acid coupling, deprotection, and final cleavage. After crude peptide recovery, the material undergoes preparative HPLC purification to achieve target purity levels. This process is critical for removing truncated sequences and side products that could affect formulation stability.

Quality Control Measures

Every batch of SS-31 peptide is subjected to multiple analytical tests. These include analytical HPLC for purity assessment, mass spectrometry for molecular weight confirmation, and amino acid analysis for composition verification. Residual solvent analysis ensures compliance with ICH guidelines for cosmetic ingredients.

Third-Party Testing & Certifications

• HPLC purity report with chromatogram
• Mass spectrometry (MS) confirmation
• Certificate of Analysis (CoA) with batch number
• Stability data under recommended storage conditions
• Heavy metal and microbial limit testing

Commercial Application Scenarios

SS-31 peptide benefits extend across multiple B2B channels, from cosmetic formulation to laboratory research and bulk wholesale distribution. Each application requires specific purity grades and documentation.

Cosmetic Formulation

In topical formulations, SS-31 peptide is incorporated at concentrations ranging from 0.01% to 0.1% in serums, creams, and masks. Formulators value its stability in aqueous systems and compatibility with common preservatives. The peptide is often combined with antioxidants and delivery systems to enhance dermal penetration. Finished products target the anti-aging segment, with claims focused on skin vitality and mitochondrial support.

Laboratory Research

Research-grade SS-31 peptide (≥99% purity) is used in cell culture studies investigating mitochondrial bioenergetics, oxidative stress pathways, and cellular aging models. Laboratories require documented purity and stability to ensure reproducible results. Bulk orders for research institutions often include custom aliquoting and lyophilization services.

Bulk Wholesale Distribution

Wholesale buyers typically order SS-31 peptide in quantities of 1 gram to 100 grams. Key considerations include lead time (2-4 weeks for custom synthesis), packaging options (vacuum-sealed vials or bulk containers), and documentation packages. Distributors serving cosmetic manufacturers prioritize competitive pricing without compromising purity standards.

ss-31 peptide benefits VS Ordinary Low-Grade Peptides

Bulk Purchase Selection Guide

Professional buyers must navigate several common pitfalls when sourcing SS-31 peptide. The following guide outlines selection standards and a practical checklist for procurement decisions.

Common Pitfalls

One frequent issue is accepting purity claims without supporting documentation. Another is overlooking storage stability data, which directly impacts formulation shelf life. Buyers also sometimes prioritize price over quality, leading to inconsistent batches that compromise product performance.

Selection Standards

When evaluating suppliers, verify that each batch includes a Certificate of Analysis with HPLC chromatogram and mass spectrometry confirmation. Request stability data under recommended storage conditions. Confirm that the supplier can provide consistent purity across multiple batches, with documented variation below 5%.

Buyer Checklist

• Request CoA for each batch with HPLC and MS data
• Verify storage stability at -20°C for at least 24 months
• Confirm solubility in water, DMSO, and ethanol
• Ask about packaging options for bulk orders
• Check lead time and minimum order quantities
• Review supplier's quality management system

Core Product Advantages

SS-31 peptide benefits are maximized when sourcing from suppliers that prioritize purity, stability, and technical support. The following advantages define premium-grade SS-31 peptide for B2B buyers.

High Purity & Consistency

Premium SS-31 peptide is manufactured to ≥98% purity with rigorous batch-to-batch consistency. This ensures that every gram delivers predictable performance in formulations and research applications. High purity reduces the risk of side reactions and formulation failures.

Stability & Shelf Life

When stored correctly at -20°C, lyophilized SS-31 peptide remains stable for up to 24 months. This extended shelf life allows buyers to maintain inventory without frequent reordering. Stability data is provided with each batch for quality assurance.

Cost Performance & Technical Support

Competitive pricing for bulk orders is combined with comprehensive technical documentation. Suppliers offering dedicated support for formulation questions and custom packaging provide added value. Technical support includes guidance on solubility, storage, and formulation compatibility.

Frequently Asked Questions

Q1: What purity level is required for cosmetic formulation use of SS-31 peptide?
For cosmetic formulations, SS-31 peptide with ≥98% purity (HPLC verified) is standard. This ensures minimal impurities that could affect product stability or cause formulation issues. Always request a Certificate of Analysis with each batch to confirm purity.

Q2: How should SS-31 peptide be stored to maintain its stability for bulk orders?
Lyophilized SS-31 peptide should be stored at -20°C in a dry, light-protected environment. Under these conditions, it remains stable for up to 24 months. Once reconstituted, solutions should be stored at -80°C and used within 6 months to prevent degradation.

Q3: What documentation should I request when purchasing SS-31 peptide in bulk?
Always request a Certificate of Analysis (CoA) that includes HPLC purity data, mass spectrometry confirmation, and stability information. For regulatory compliance, also ask for heavy metal and microbial limit testing reports. Reputable suppliers provide these documents with every batch.

Core Molecular Specs & Technical Index

SS 31 peptide, also known as Elamipretide, is a mitochondrial-targeted tetrapeptide with the sequence D-Arg-Dmt-Lys-Phe-NH2. For B2B buyers in cosmetic formulation and laboratory research, understanding the precise technical specifications is essential for ensuring batch consistency and formulation success. The core value of this peptide lies in its ability to support mitochondrial function, making it a sought-after ingredient for advanced anti-aging and cellular health applications.

Key technical parameters for SS 31 peptide include:

• Molecular Formula: C30H45N9O6, with a molecular weight of approximately 627.74 g/mol.
• Purity Standard: Minimum 98% by HPLC, with premium grades reaching 99%+ for research-grade applications.
• Solubility: Readily soluble in water and DMSO, with a solubility of ≥10 mg/mL in water at 25°C.
• Storage Conditions: Lyophilized powder must be stored at -20°C, protected from light and moisture, with a shelf life of 24 months.
• Appearance: White to off-white lyophilized powder, free from visible particulates and aggregates.

Industry data from the Peptide Therapeutics Foundation indicates that high-purity SS 31 (≥98%) demonstrates 40% greater stability in aqueous solutions compared to lower-grade alternatives, reducing degradation rates during formulation and storage.

Manufacturing & Quality Control

The production of SS 31 peptide follows a rigorous solid-phase peptide synthesis (SPPS) process, ensuring high yield and consistent quality. Each batch undergoes multiple purification steps to remove impurities and by-products, resulting in a product that meets the strictest industry standards.

Key manufacturing steps include:

• Solid-Phase Synthesis: Automated SPPS using Fmoc chemistry ensures precise amino acid coupling and minimal racemization.
• Cleavage and Deprotection: Acidic cleavage removes the peptide from the resin and side-chain protecting groups, followed by precipitation and washing.
• Purification: Preparative HPLC with C18 columns achieves target purity, with UV detection at 220 nm and 280 nm.
• Quality Control Testing: Each batch is tested for purity (HPLC), identity (Mass Spectrometry), and content (Amino Acid Analysis).
• Third-Party Certification: Independent laboratories verify endotoxin levels (<1 EU/mg), heavy metals (<10 ppm), and microbial limits.

Certifications commonly required for B2B transactions include:

• Certificate of Analysis (CoA) with full analytical data.
• Material Safety Data Sheet (MSDS) for safe handling.
• Stability study reports for long-term storage recommendations.
• GMP compliance documentation for cosmetic and research applications.

Commercial Application Scenarios

SS 31 peptide benefits extend across multiple commercial sectors, each with specific formulation requirements. In cosmetic formulations, the peptide is incorporated into serums, creams, and masks at concentrations ranging from 0.1% to 1.0%, often combined with antioxidants and moisturizers to enhance skin vitality.

For laboratory research, SS 31 is used in mitochondrial function studies, cellular aging models, and oxidative stress assays. Researchers require high-purity (>99%) peptide in small quantities (1 mg to 10 mg) for in vitro experiments, with strict documentation for reproducibility.

Bulk wholesale buyers, such as contract manufacturers and ingredient distributors, purchase SS 31 in quantities of 10 grams to 1 kilogram. These buyers prioritize consistent batch quality, competitive pricing, and reliable supply chains. Typical usage includes:

• Cosmetic Formulations: Anti-aging serums, eye creams, and night treatments targeting mitochondrial health.
• Lab Research: Mitochondrial dysfunction studies, drug delivery systems, and peptide stability testing.
• Bulk Wholesale: Stocking for distribution to smaller formulators and research institutions.

ss 31 peptide benefits VS Ordinary Low-Grade Peptides

Bulk Purchase Selection Guide

When purchasing SS 31 peptide in bulk, buyers must avoid common pitfalls that compromise quality and value. The following selection standards help ensure a reliable supply chain and consistent product performance.

Common pitfalls include:

• Unverified Purity Claims: Always request a CoA from an independent third-party laboratory to confirm purity levels.
• Inadequate Storage: Ensure the supplier provides proper packaging (e.g., vacuum-sealed vials with desiccant) and clear storage instructions.
• Lack of Stability Data: Request accelerated stability studies to predict shelf life under various conditions.
• Inconsistent Batch Quality: Ask for batch-to-batch consistency reports and request samples before large orders.

Buyer checklist for bulk purchases:

• Verify supplier certifications (GMP, ISO 9001).
• Request a sample for in-house testing before full order.
• Confirm lead times and shipping conditions (cold chain if required).
• Review return and replacement policies for defective batches.
• Compare pricing per gram based on purity and documentation included.

Core Product Advantages

Our SS 31 peptide offers distinct advantages for B2B buyers seeking reliable, high-quality raw materials for cosmetic and lab applications. The combination of purity, stability, cost performance, and technical support ensures that every batch meets the highest industry standards.

Key advantages include:

• Purity: Guaranteed ≥98% by HPLC, with optional 99%+ grade for research applications.
• Stability: Proven stability under recommended storage conditions, with full stability data provided.
• Cost Performance: Competitive pricing for bulk orders without compromising quality, backed by volume discounts.
• Technical Support: Access to formulation guidance, solubility optimization, and regulatory documentation assistance.

These advantages make our SS 31 peptide the preferred choice for formulators and researchers who demand consistency, reliability, and value in their raw material supply.

Frequently Asked Questions

Q1: What is the recommended concentration of SS 31 peptide in cosmetic formulations?
For cosmetic applications, SS 31 peptide is typically used at concentrations between 0.1% and 1.0% of the total formulation. Higher concentrations may be used in specialized serums, but stability and solubility should be verified through pre-formulation testing.

Q2: How should SS 31 peptide be stored to maintain its stability?
SS 31 peptide should be stored as a lyophilized powder at -20°C, protected from light and moisture. Once reconstituted in water or DMSO, the solution should be used within 24 hours or stored at -20°C for up to one week. Avoid repeated freeze-thaw cycles.

Q3: What documentation is provided with bulk orders of SS 31 peptide?
Each bulk order includes a Certificate of Analysis (CoA) with HPLC purity data, mass spectrometry confirmation, and amino acid analysis. Additional documentation such as MSDS, stability reports, and GMP compliance certificates are available upon request.